| Seller/manufacturer warranty | 36 months. |
| Type | motherboard |
| Model | ASUS TUF GAMING B450-PLUS II |
| Series | ASUS TUF GAMING |
| Release year | 2021 |
| Form factor | Standard-ATX |
| Height | 305 mm |
| Width | 244 mm |
| Socket | AM4 |
| AMD Chipset | AMD B450 |
| Compatible AMD processor cores | Matisse, Picasso, Pinnacle Ridge, Raven Ridge, Renoir, Summit Ridge, Vermeer |
| Supported memory type | DDR4 |
| Supported memory form factor | DIMM |
| Number of memory slots | 4 |
| Number of memory channels | 2 |
| Maximum memory | 128 GB |
| Maximum memory frequency (JEDEC / non-overclocked) | 2666 MHz |
| Overclocked RAM frequency | 2800 MHz, 3000 MHz, 3200 MHz, 3400 MHz, 3466 MHz, 3533 MHz, 4400 MHz |
| PCI Express Version | 3.0 |
| PCIe x16 slots | 1 x PCIe 2.0 (in x4 mode), 1 x PCIe 3.0 (in x16 mode) |
| SLI/CrossFire support | CrossFire X |
| Number of cards in SLI / Crossfire | 2 pcs. |
| Number of PCI-E x1 slots | 3 |
| NVMe support | yes |
| PCI Express drive version | 3.0 |
| Number of M.2 connectors | 2 |
| M.2 (M) slots, PCIe processor lines | 1 x 2242/2260/2280/22110 (SATA/PCIe 3.0 x4) |
| M.2 (M) slots, PCIe chipset lines | 1 x 2242/2260/2280 (PCIe 2.0 x4) |
| Number of SATA ports | 6 |
| SATA RAID operating mode | 0, 1, 10 |
| Other drive connectors | no |
| USB Type-A Ports | 1 x USB 3.2 Gen 2, 2 x USB 2.0, 4 x USB 3.2 Gen 1 |
| USB Type-C ports | 1 x USB 3.2 Gen 2 |
| Video outputs | 1 x DisplayPort |
| Number of network ports (RJ-45) | 1 |
| Number of analog audio connectors | 5 |
| Digital audio ports (S/PDIF) | TOSLINK (S/PDIF optical) |
| SMA connectors (for Wi-Fi antenna) | no |
| PS/2 ports | no |
| Internal USB Type-A connectors | 1 x USB 3.2 Gen 1 (19 pin), 2 x USB 2.0 (9 pin) |
| Internal USB Type-C connectors | no |
| CPU cooling power connectors | 1 x 4 pin |
| Case fan headers (3 pin) | no |
| Connectors 5V-D-G (3 pin) for ARGB backlight | no |
| Connectors 12V-G-R-B (4 pin) for RGB backlight | 2 |
| M.2 (E) connector for wireless modules | no |
| LPT interface | no |
| Sound design | 7.1 |
| Sound adapter chipset | Realtek ALC S1200A |
| Network adapter speed | 1 Gbps |
| Network adapter | Realtek L8200A |
| Wi-Fi standard | no |
| Bluetooth version | no |
| Wireless adapter | no |
| Main power connector | 24 pin |
| CPU power connector | 1 x 8 pin |
| Number of power phases | 8+2 |
| Passive cooling | VRM zone, chipset |
| Active cooling | no |
| Buttons on board | BIOS FlashBack button |
| Illumination of board elements | yes |
| Backlight Sync Software | ASUS Aura Sync |
| Additional features | SafeSlot technology |
| Contents | 2 x SATA cable, software disk, documentation, back plate, fasteners for M.2 connector |
| Country of origin | China |
| Case fan headers (4 pin) | 3 |
| Box length | 34 cm |
| Box width | 27 cm |
| Box height | 7 cm |
| Number of PCB layers | 3 |
| Connectors for the liquefied liquid pump (4 pin) | 1 |
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